SPRAVATO™ FDA Approved ESKETAMINE
Say Hello to a New You
SPRAVATO® is the first FDA approved prescription nasal spray used for treatment resistant depression.
SPRAVATO™ FDA Approved ESKETAMINE
Say Hello to a New You
About Esketamine
History of Spravato
In 2019, the FDA granted approval for SPRAVATO®, an esketamine-derived nasal spray designed for adults grappling with Treatment Resistant Depression and suicidal ideation. This significant milestone reinforces the medical community’s confidence in the potency of the Ketamine molecule, showcasing its capability to deliver substantial and prompt relief. This nasal spray represents a new frontier in treatment options, providing hope and possibilities for those navigating the complexities of depression. Esketamine plus an oral antidepressant has been found to relieve the symptoms of depression within hours, rather than the usual weeks most antidepressants can take.
What is Spravato?
Spravato is an N-methyl-D-aspartate (NMDA) receptor antagonist that is believed to work differently by action on a pathway in the brain where glutamate, a brain chemical, works with other brain chemicals to balance well-being and depression. By blocking the NMDA receptor, esketamine leads the formation of new neural connections and the restoration of neural plasticity.
Is SPRAVATO® Right For You?
- If you have tried or are currently taking two or more anti-depressants you may have Treatment Resistant Depression
- You’ve tried many options over the years and can’t seem to find relief from your depression and have been diagnosed with Major Depressive Disorder
- You have suicidal ideation
If any of these resonate with you, call us today to schedule an evaluation with one of our psychiatric medical providers at Hopemark Health.
Why Hopemark Health?
Hopemark Health proudly maintains REMs certification as a trusted Spravato treatment center, a status we’ve held since the medication’s introduction in March 2019. With extensive experience surpassing many other clinics, our consistently high patient volumes attest to our expertise and dedication.
In addition, we’ve been honored as the fastest-growing Spravato treatment center in Chicago.
Where is Spravato Available? *Spravato is only available through a restricted program called the Spravato REMS (Risk Evaluation and Mitigation Strategy). It is administered intranasally while under clinical supervision in a REMS certified Spravato treatment center. Patients can only receive treatment from one REMS certified Spravato treatment center.
Your Spravato Treatment Journey at Hopemark Health
Taking SPRAVATO® nasal spray is a straightforward process, conducted under the supervision of our healthcare professionals in a comfortable healthcare setting. Here’s what you can expect:
Your journey at Hopemark Health begins with an evaluation with one of our psychiatric medical providers. During this appointment the provider will inquire about your medical and mental health treatment history including medications, treatments and symptoms. If you meet the criteria for Spravato the provider will recommend you for treatment. Once a complete history is gathered, your provider will lay out the options, and together you will create the plan to move forward.
Insurance covers Spravato in most cases but does require pre-authorization from your insurance carrier prior to beginning treatment. This process can take time to complete.
Once approved, the path to a new you begins! Your healthcare provider will determine the appropriate dosage and schedule for your SPRAVATO® treatment. Each session lasts about 2 hours. You will self-administer SPRAVATO® nasal spray, following the instructions provided by our healthcare provider. They will demonstrate the proper technique for using the nasal spray device.
- Induction Phase: 2 sessions a week for 4 weeks
- Optimization Phase: 1 session a week for an additional 4 weeks
- After this 8-week treatment program, some patients may benefit from maintenance treatment of 1 session every 1-2 weeks.
Throughout your SPRAVATO® session, our healthcare team will closely monitor your well-being. Patients are monitored with state-of-the-art Caretaker System to see real time blood pressure, heart rate, and oxygen saturation measurements. We’ll assess your readiness to leave the healthcare setting after each use.
To minimize the risk of side effects, it’s crucial to follow specific guidelines, such as refraining from eating for at least four hours before using SPRAVATO® and avoiding liquids for at least 30 minutes prior. You will discuss these guidelines with your provider prior to your appointment.
If you’re taking nasal corticosteroids or nasal decongestants, ensure you take these medications at least one hour before using SPRAVATO® to prevent potential interactions. Please discuss with your provider prior to your appointment.
You can not drive or operate machinery immediately after so it is important to arrange for a ride home after your SPRAVATO® treatment.
What to Expect with SPRAVATO®
Patients are observed and monitored by our expert nursing staff using state-of-the-art Caretaker Systems to see real time blood pressure, heart rate, and oxygen saturation measurements. You will be in a private room with the options to relax with an eye mask and listen to music and / or a TV when desired.
You may experience temporary side effects:
- Sedation
- Dissociation (including out-of-body experience, distortion of time and space, illusions, derealization)
- Dizziness
- Nausea (we have medication available to help with this)
- Increased Blood Pressure
- Hypoesthesia (loss of sensation in a body part)
- Cognitive Impairment (reduced attention, judgment, thinking, reaction speed and motor skills)
You will be ready to go home after the medical staff clears you for release. You cannot drive home, so please secure a ride with a friend or family member.
At Hopemark Health, your comfort, safety, and well-being are paramount. Our experienced healthcare professionals are dedicated to supporting you throughout your SPRAVATO® treatment journey. If you have any concerns or questions, please don’t hesitate to reach out to our team.
Insurance Coverage
Insurance coverage for Spravato can vary significantly depending on you specific plan and policy. There are two ways that Spravato may be covered under a patient’s insurance plan.
- Medical Benefits: Some insurance plans cover Spravato as a part of your Medical benefits.
- Pharmacy Plan: Alternatively, it may be covered under your pharmacy benefits.
Since Spravato requires administration by a healthcare professional and 2-hour monitoring, there are two billing aspects:
- Medication Cost: This includes the cost of the medication itself, which can be covered through pharmacy or medical benefits.
- Clinical Monitoring: The 2-hour observation and monitoring by our clinical team.
At Hopemark, we conduct a through investigation of each patient’s insurance plan and benefits to determine coverage and any potential out-of-pocket cost. Patients will receive an estimated expected out-of-pocket cost before starting treatment. Additionally, we assist patients in exploring options, including the SPRAVATO withMe program, which helps reduce cost for those with no insurance coverage or lower out-of-pocket expenses.
Learn more about SPRAVATO® at spravato.com